Gene therapy and solid-organ transplantation
نویسندگان
چکیده
منابع مشابه
Alemtuzumab induction therapy in solid organ transplantation
Alemtuzumab (Campath) is a monoclonal antibody that has a profound lymphocyte-depleting effect, targeting the CD52 antigen that is present on all lymphocytes. Alemtuzumab has been used for the treatment of chronic lymphocytic leukaemia and various autoimmune disorders, and has also shown potential as an induction agent in the prevention of rejection following solid organ transplantation. Alemtu...
متن کاملRecent Progress in Cell Therapy in Solid Organ Transplantation
There has been ample of preclinical and animal studies showing efficacy and safety of using various cells, such as stem cells or T regulatory cells, after transplantation for tissue repair, immunosuppression or tolerance induction. However, there has been a significant progress recently using cell therapy in solid organ transplantation in small clinical trials. Recent results have been promisin...
متن کاملCoccidioidomycosis in solid organ transplantation.
Coccidioidomycosis is an endemic fungal infection of the southwestern United States. Normally a self-limited infection in healthy hosts, coccidioidomycosis can become a serious complication in patients who have had solid organ transplantation. Among patients whose solid organ transplantation was complicated by coccidioidomycosis, the infection has a variety of clinical presentations. Disseminat...
متن کاملIntroduction to Solid Organ Transplantation
Organ transplantation has been the subject of ancient myths dating back to the twelfth century. The modern era of transplantation began in the early 1900s with the development of surgical techniques for constructing vascular anastomoses [ 1 ] leading to successful kidney transplantation in dogs in 1902 [ 2 ]. The fi rst series of human kidney transplants were performed in the Ukraine beginning ...
متن کاملMacrophages in solid organ transplantation
Macrophages are highly plastic hematopoietic cells with diversified functions related to their anatomic location and differentiation states. A number of recent studies have examined the role of macrophages in solid organ transplantation. These studies show that macrophages can induce allograft injury but, conversely, can also promote tissue repair in ischemia-reperfusion injury and acute reject...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2002
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.2002.0610s1056.x